2022 Prize Shortlist

The shortlist includes 65 organisations and individuals from 26 countries.

The judging panel will now deliberate on the winners, which will be publicly announced at the Lush Prize Conference and Awards Ceremony in November.

 

Lobbying

Prof Jae Sung Hwang
South Korea
National Center for Cosmetic R&D – Development of an animal alternative efficacy test method

Dr Alison Gray
UK
Policy intervention to replace animal derived antibodies with animal friendly affinity reagents

Center for Contemporary Sciences
USA
CCS Lobbying to End Animal Testing

Center for a Humane Economy and Animal Wellness Action
USA
The FDA Modernization Act of 2021

Dr Marize Campos Valadares
Brazil
Lobbying for the best science available and building confidence in New Approach Methodologies in safety science

The New Zealand Anti-Vivisection Society (NZAVS)
Aotearoa/New Zealand
Removal the social license of the Forced Swim Test in NZ

Omica Research and Innovation Ltd Comp
Turkiye/Turkey
Omic-A Skin

 


Political Achievement

Jytte Guteland MEP
Sweden

Tilly Metz MEP
Luxembourg

In-soon Nam
South Korea

 


Public Awareness – Current

Phoenix Zones Initiative
USA
Transforming Medical Research

Carlota Saorsa
Spain
Investigation at Vivotecnia laboratory

Jessica Lohmann
Germany
Lily Bowers and the Uninvited Guest

Humane Society International
USA
Save Ralph

Beagle Rescue Network
South Korea
Stopped animal testing on service dogs

Dr Costanza Rovida and Jean Knight
Germany
A systematic review on the conflicts between REACH and the EU Cosmetic Regulation: from awareness to action

Animal Testing
France
Investigating about households products experiments

 


Public Awareness – Future

ONG Te Protejo
Chile
Banning animal testing for cosmetics in Argentina

Altertox SRL
Belgium
Playing and coding for alternatives to animal testing

Animal Rights VZW
Belgium
Annual ‘Pure Evil’ award campaign

 


Science

Dr Baeckkyoung Sung
Germany
In silico toxicology platform based on endocrine organ-on-a-chip systems

Dr Marie-Gabrielle Zurich
Switzerland
Building a strategy to assess the neurotoxicity of solvents

Artificial Intelligence Innovation Lab
USA
Knowledge-guided deep learning models of drug toxicity improve prediction and interpretation

Joint Project team of TissUse, Cosmetics Europe and Beiersdorf, namely: Katrin Brandmair, Thi Phuong Tao, Silke Gerlach, Nicky Hewitt, Jochen Kühnl and Ilka Maschmeyer
Germany
Demonstrating metabolism of a hair dye in the skin and liver in co-culture

Dr Daniel André Gonçalves Ferreira
Portugal
A Fast Alternative to Soft Lithography for the Fabrication of Organ-on-a-Chip Elastomeric-Based Devices and Microactuators

Dr Sejoong Kim
South Korea
Development of 3D tissue chip models mimicking multiple organs

The Acute Systemic Toxicity team within RTI International
USA
Mapping mechanistic pathways of acute oral systemic toxicity using chemical structure and bioactivity measurements

AlveoliX AG
Switzerland
A barrier-on-chip with integrated 3D stretching: an alternative predictive tool to support decision making

CN Bio Innovations
UK
Organ-on-a-Chip for better model of human physiology

Computational toxicology teams at Instem and Innovatune
USA
Addressing the acceptance of in silico toxicology

Micro-Tissue Engineering (MicroTE) Lab / Queensland University of Technology
Australia
Organs-on-chips (OoCs) for modelling drug responses mediated by multi-cellular interactions

Dr.-Ing. habil. Joachim Wiest
Germany
Systems engineering of microphysiometry

European Commission Joint Research Centre, Directorate F- Health, Consumers and Reference Materials
Italy
Use of human cell-based assays anchored to mechanistically relevant key events as a tool for the regulatory testing of developmental neurotoxicity

OECD Chemical Safety Programme
France
Efforts towards international harmonization of NAMs

Dr. Zhongze Gu
China
Develop Automatic Organs-on-Chip Systems

ReproTracker Team, Developmental Toxicology Department, Toxys B.V.
Netherlands
ReproTracker: an in vitro alternative to animal models for developmental toxicity testing

EU-ToxRisk – mitotoxicity case study team
Netherlands
New approach methods (NAMs) supporting read-across: Two neurotoxicity AOP-based IATA case studies.

 


Training

Stichting Proefdiervrij
Netherlands
Proefdiervrij Venture Challenge

Centre for Predictive Human Model Systems, Atal Incubation Centre-Centre for Cellular and Molecular Biology (AIC-CCMB))
India
Training and education in 1R approaches in India

Animal Free Research UK
UK
Summer Student Programme: Next Generation

LIALT Laboratorio de Investigación Alternativa
Mexico
3D Tissues: An alternative to animal testing

Animal Welfare Academy of the German Animal Welfare Federation
Germany
Replacing Fetal Bovine Serum (FBS) in Research & Testing

EU Reference Laboratory for alternatives to animal testing (EURL ECVAM)
Italy
Introducing the Three Rs in education programmes and curricula

The European Society of Toxicology In Vitro (ESTIV)
Netherlands
ESTIV Applied Training Course

Ärzte gegen Tierversuche e.V.
Germany
NAT-Database: Raising public awareness for Non-Animal Technologies to promote a human-based research generating human-relevant results

Prof.dr. Pamela Bejdić, University of Sarajevo-Veterinary Faculty
Bosnia and Herzegovina
Dual Education System As a New Tool for Improving Practical Skills and Vocational Training of Veterinary Students

 


Young Researcher

Dr Supratik Kar, Jackson State University
USA
In Silico modeling of Mixtures toxicity of hazardous Chemicals through multitude approaches

Xuelian Jia, Rutgers-Camden, Center for Computational and Integrative Biology
USA
Development of Mechanism-driven Virtual Adverse Outcome Pathway (vAOP) for Hepatotoxicity

Prof. Dr. Francesca Grisoni, Eindhoven University of Technology
Netherlands
Combining artificial intelligence and human organoids for animal-free drug discovery: towards a paradigm shift

Dr Andreia Verissimo Luis, THT Biomaterials GmbH
Austria
We make human placenta great again and an animal-free pepsin!

Dr Chrysanthi-Maria Moysidou, University of Cambridge, Dept of Chemical Engineering and Biotechnology
UK
Bioelectronic technology and Organs-on-Chips synergy: A 3D in vitro platform sheds light in the human microbiome-gut-brain axis interactions

Artur Silva, Federal University of Goiás
Brazil
Lung-sens-on-a-chip model for mechanistic assessment of chemically-induced pulmonary sensitization: Providing building blocks for the respiratory allergy AOP

Dr Sara Tirendi, University of Genoa
Italy
Improvement of an innovative 3D human-based model useful to identify the key events behind glaucoma pathogenesis

Dr Carlo Alberto Paggi, University of Twente
Netherlands
A joint-on-chip model to tackle arthritis

Farzaneh Fayazbakhsh, Tehran University of Medical Sciences
Iran
Using the microfluidic device for inducing oxidative stress on endothelial cells and assessing of antioxidant activity of gold nanoparticles attached to polyphenols

Dr Stefanie Klima, University of Konstanz
Germany
Advancing a human stem cell-derived test system for neurotoxicity

Dr Stephen Evans, Swansea University
UK
Development of healthy and immunocompromised dynamic lung co-culture models for toxicity testing

Dr Sebastian Eggert, cellasys GmbH
Germany
Identification of serum-free cell culture media formulations with automated and standardized microphysiometry

Thi Phuong Tao, TissUse GmbH
Germany
Use of a dynamic 3-organ co-culture in the HUMIMIC Chip3 to assess endocrine disrupting properties of test compounds

Dr Pouria Fattahi, University of Pennsylvania
USA
Inhalation toxicology‐on‐a‐chip

Dr Arunima Sengupta, ARTORG Center, University of Bern
Switzerland
Smoking alveolosphere on-chip to study COPD and lung cancer exacerbations

Dr Arthur de Carvalho e Silva, University of Birmingham
UK
Integrating physiologically-based pharmacokinetic modelling and ‘omics data to derive health-based guidance values for perfluorinated chemicals

Dr Sudeep Joshi, The Francis Crick Institute and King’s College London
UK
A robotic process automation system for biomanufacturing animal-free in-vitro 3D tissue and organoid models for drug screening

Dr Shagun Krishna, National Toxicology Program (DNTP), National Institute of Environmental Health Services (NIEHS)
USA
Computational Cardiotoxicology: Building an AI-assisted alternative method-based toxicity screening pipeline

Dr Paul Holloway, University of Oxford
UK
Using patient derived cells to build brain blood vessels in a chip: developing a new model to study cerebral small vessel disease and stroke